Stem cells are at the forefront of one of the most fascinating and revolutionary areas of medicine today. Doctors recognize that stem cells have the potential to help treat numerous diseases by generating healthy new cells and tissue.
As a parent, you want to protect your family. At your baby’s birth, you have the unique opportunity to safeguard the health of the ones you love by storing his/her precious cord blood stem cells.
Stem cells in your baby’s cord blood have the potential to be used in the treatment of many diseases today. Stem cells could be used to treat haematopoietic and genetic disorders. In a cord blood transplant, stem cells are infused into a patient’s bloodstream where they go to work - healing and repairing damaged cells and tissue. Upon successful engraftment of the stem cells, the patient’s blood and immune system are regenerated.
There are a wide range of diseases that are treatable with stem cells derived from cord blood and other sources of similar type of stem cells (Haematopoietic Stem Cell), like bone marrow and peripheral blood, including stem cell disorders, acute and chronic forms of leukemia, myeloproliferative disorders, and many more.
In addition to the host of conditions that can now be treated, it is the potential of stem cell treatments that holds the most excitement as research continues to uncover new possibilities. The potential and efficacy of treating diseases with stem cells are real.
Diseases Treated with Stem Cells
The following is a list of some of the diseases that have been treated with cord blood and other sources of similar type of stem cells (Haematopoietic Stem Cell), like bone marrow and peripheral blood. Stem cell therapies continue to change and evolve quickly.
Download the list of treatable diseases.
BLOOD CANCERS
- Acute Biphenotypic Leukaemia
- Acute Myelogenous Leukaemia
- Acute Undifferentiated Leukaemia
- Acute Myelofibrosis
- Agnogenic Myeloid Metaplasia
- Chronic Myelogenous Leukaemia
- Chronic Lymphoblastic Leukaemia
- Essential Thrombocythemia
- Juvenile Myelomonocytic Leukaemia
- Juvenile Chronic Myelogenous Leukaemia (Allo)
- Histiocytic Neoplasms
- Multiple Myeloma
- B-cell Acute Lymphoblastic Leukaemia
- T-cell Acute Lymphoblastic Leukaemia
- Myelodysplastic syndrome
- Other Myeloproliferative Neoplasms
- Polycythemia Vera
- Plasma Cell Leukaemia
- Refractory Anaemia
- Refractory Anaemia with Excess Blasts
- Refractory Anaemia with Excess Blasts in Transformation
- Refractory Anaemia with Ringed Sideroblasts (Sideroblastic Anaemia)
- Systemic Mastocytosis
- Waldenstrom's Macroglobulinemia
NON-MALIGNANT BLOOD DISORDERS
- Congenital Amegakaryocytosis Thrombocytopenia
- Aplastic Anaemia
- Chediak-Higashi Syndrome
- Congenital Dyserythropoietic Anaemia
- Diamond-Blackfan Syndrome
- DiGeorge Syndrome
- Dyskeratosis Congentia
- Evans Syndrome
- Fanconi's Anaemia
- Glanzmann'sThrombasthenia
- Gunther's Disease (erythropoietic porphyria)
- Hereditary BM failure syndromes
- Hemophagocytic Lymphohistiocytosis
- Leukocyte Adhesion Deficiency
- Pearson's Syndrome
- Paroxysmal Nocturnal Hemoglobinuria
- Pure Red Cell Aplasia
- Sickle Cell Anaemia
- Shwachman Diamond Syndrome
- Thalassemia Major
SOLID TUMORS
- Hodgkin Lymphoma
- Non-Hodgkin Lymphoma
- Langerhans' Cell Histiocytosis
- Neuroblastoma
- Non Hodgkin Lymphoma (Burkitt’s Lymphoma)
- Retinoblastoma
- Medulloblastoma
- Wilms Tumor
IMMUNE DISORDERS
- Ataxia-Telangiectasia (Allo)
- Chediak Higashi Syndrome
- Chronic Granulomatous Disease
- Common Variable Immunodeficiency
- Chronic Granulomatous Diseases
- Cartilage-Hair Hypoplasia
- DiGeorge Syndrome
- Evans syndrome
- Gunther's Disease (Congential Erythropioet Protoporphyria)
- Hemophagocytic Lymphohistiocytosis
- IKK Gama Deficiency (NEMO Deficicency)
- IKK Gamma Dificiency (NEMO Deficiency)
- IPEX Syndrome
- Kostmann Syndrome(Infantile Genetic Agranulocytosis)
- Myelokathexis
- Leukocyte Adhesion Deficiency
- Omenn Dysgensis
- Reticular Dysgenesis
- Neutrophil Actin Deficiency (Allo)
- Severe Combined Immune Deficiency (SCID)
- SCID with Adenosine Deaminase Deficiency (ADA SCID)
- SCID which is X Linked
- SCID with absence of T & B Cells
- SCID with absence of T Cells, Normal B Cells
- Shwachman-Diamond Syndrome
- Systemic Mastocytosis
- X Linked Lymphoproliferative Disease (Duncan's Syndrome)
- X linked Hyper IgM Syndrome
- Wiskott-Aldrich Syndrome
Banking cord blood does not guarantee that the cells will provide a cure or be applicable in every situation. Use will be ultimately determined by the treating physician.
Clinical Trials
With the advancement of stem cell* research, the potential for future use of stem cell grows.
Below is a list of diseases currently under clinical trials. These are diseases for which stem cell* treatments appear to be beneficial, but have not been adopted as standard therapy. For some of these diseases, stem cell transplants only slow the progression of the disease, but do not produce a cure. For other diseases, stem cell treatments may help effect a cure, but further research is needed to determine the best candidate patients for stem cell therapy, the optimum stem cell dosage, the optimum method of cell delivery, etc.
For some patients, clinical research trials are an alternative avenue for receiving new and promising therapies that would otherwise be unavailable. Patients with difficult-to-treat or ‘incurable’ diseases, such as HIV or certain types of cancer, may choose to participate in clinical research trials should standard therapies prove to be ineffective. Clinical research trials are sometimes lifesaving.
- Alzheimer's Diseases
- Amyotrophic Lateral Sclerosis
- Autism
- Battlefield Trauma
- Brain Tumor
- Cartilage Hair Hypoplasia
- Cartilage Repair
- Cleft Palate Repair (Alveolar)
- Cerebral palsy
- Compartment Syndrome
- Crohn's disease
- Critical Limb Ischemia
- Diabetes Type 1
- Epidermolysis Bullosa
- Ewing Sarcoma
- Graft-versus-Host Disease (GvHD)
- Hypoxic Ischemic Encephalopathy (HIE)
- Hearing Loss
- HIV
- Ischemic Stroke
- Ischemic Heart Disease
- Lupus
- Multiple Sclerosis
- Myocardial Infarction
- Open cardiac surgery for congenital heart diseases
- Ovarian Cancer
- Rheumatoid Arthritis
- Spinal cord injury
- Scleroderma
- Testicular Tumour
- Tissue Engineered Vascular Grafts for cardiac defects
- Traumatic Brain Injury
For the latest information, please visit www.clinicaltrials.gov
Experimental Treatments
These are randomised controlled trials conducted in a scientific laboratory involving in-vitro (test tube or cell culture) and in-vivo (animal) work. The experimental trials are in place to assist and to decide whether they have scientific merit for further development / progression to clinical trials.
- Alzheimer's Disease
- Amyotrophic lateral sclerosis
- Congenital hydrocephalus
- Huntington's Disease
- Liver cirrhosis
- Parkinson's Disease
- Traumatic Brain Injury
The above list of diseases is a compilation from the above websites and other sources such as medical literatures and journals. Kindly approach us at (65) 6238 0808 or info@mm.cordlife.com to request for a particular medical journal / literature.
*Stem cells mentioned here comprises of other cell lines such as Mesenchymal stem cells. The clinical trials and experimental treatments listed above may be using other lines of stem cells, and not only haematopoietic stem cells.
DCR No: SLB/Potential Treatment >80 Diseases/PM-095/Rev00
